Curcuma marque blanche 60 gelules CurcuGREEN® BCM-95®

Description

Curcuma marque blanche en pilulier blanc de 60 capsules sans étiquette

Retrouvez tous nos compléments alimentaires en marque blanche ici

Ingrédients

Pour la dose journalière recommandée, soit 2 gélules :

Curcuma (Extrait de Curcuma Longa) 150mg
Dont 95% Complexe Curcuminoïdes 42,5mg
Dont Curcumine 97,5mg

Autres ingrédients : gomme d’acacia, enveloppe végétale (hypromellose)

Allergènes : Fabriqué sur un équipement pouvant contenir des traces de céleri, crustacés, poissons, mollusques, gluten, sésame, lait, œuf, soja et sulfites.

Conseils d'utilisation

Prendre 1 capsule au petit déjeuner et au déjeuner avec un grand verre d’eau.

Avertissements

Ce produit est un complément alimentaire et ne se substitue pas à un régime alimentaire sain et varié. Produit reservé aux adultes. Déconseillé aux personnes de moins de 18 ans, aux femmes enceintes, ou allaitantes. Respectez la dose journalière recommandée (soit 2 gélules). En cas de traitements médicamenteux, demandez conseil à votre médecin ou votre pharmacien. Déconseillé chez les personnes sous traitement anticoagulant, anticancéreux et/ou immunosuppresseurs et/ou souffrant de pathologies des voies biliaires.

Etudes Cliniques

1	Effect of citrus polyphenol-and curcumin-supplemented diet on inflammatory state in obese cats. Br J Nutr. 2011 Oct; 106 Suppl 1: S198-2011.
2.	A Randomized, Pilot study to assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis. Phytotherapy Research 2012; OI:10.1002/ptr.4639
3.	Synergistic and additive effects of modified citrus pectin with two Poly botanical compounds, in the suppression of invasive behavior of human breast and prostate cancer cells. Integr Cancer Ther. 2013 Mar;12(2):145-52. Epub 2012 Apr 24.
4.	Pilot Clinical Trial of Radioprotective Effects of Curcumin Supplementation in Patients with Prostate Cancer. Hejazi et al., J Cancer Sci Ther 2013,
5.	Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis Molecular medicine reports, 2013
6.	Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. Phytother Res. 2014 Apr;28(4):579-85.
7.	Curcumin for the treatment of major depression: a randomised, double-blind, placebo controlled study. J Affect Disord. 2014;167:368-75.
8.	Curcumin Suppresses Crosstalk between Colon Cancer Stem Cells and Stromal Fibroblasts in the Tumor Microenvironment: Potential Role of EMT. PLoS ONE 9(9): e107514.
9.	Curcumin Chemosensitizes 5-Fluorouracil Resistant MMR-Deficient Human Colon Cancer Cells in High Density Cultures. PLoS ONE 9(1): e85397.
10.	Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer. BMC Cancer. 2015 Apr 10;15:250.
11.	Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer. Cancer Prev Res (Phila). 2015 May;8(5):431-43.
12.	Curcumin and major depression: A randomised, double-blind, placebo-controlled trial investigating the potential of peripheral biomarkers to predict treatment response and antidepressant mechanisms of change. European Neuropsychopharmacology , Volume 25 , Issue 1 , 38 – 50
13.	Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. Carcinogenesis. 2015 Mar;36(3):355-67.
14.	BCM-95® (CURCUGREEN®) and (2-hydroxypropyl)-ß-cyclodextrin reverse autophagy dysfunction and deplete stored lipids in Sap C-deficient fibroblasts. Hum Mol Genet. 2015 Apr 29.
15.	Evaluation of antidepressant like activity of Curcumin and its combination with Fluoxetine and Imipramine: An acute and chronic study, Acta poloniae pharmaceutica ñ drug research, vol. 68 no. 5 pp. 769-775, 2011
16.	The use of an anti-inflammatory supplement in patients with chronic kidney disease. Journal of Complementary and Integrative Medicine. 2013 Jul 1;10(1):143-52.
17.	Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression. Carcinogenesis. 2017 Oct 1;38(10):1036-46.
18.	A Pilot Cross-Over Study to Evaluate Human Oral Bioavailability of BCM-95® (CURCUGREEN®) (Biocurcumax™), A Novel Bioenhanced Preparation of Curcumin, Indian J Pharm Sci 2008;70(4):445-449
19.	6-month double-blind, placebo-controlled, pilot clinical trial of curcumin in patients with Alzheimer’s disease, J Clin Psychopharmacol, 2008, 28:110-113
20.	Curcumin effects on Blood Lipid profile in a 6-month human Study, Pharmacological Research 56 (2007) pg 509-514
21.	Bioavailability of BiocurcumaxTM (BCM-095TM), Spice India 2006 (Sept);11-15
22.	Enhancing the Absorption of Curcuminoids, Spice India 2005(July); 23-26
23.	Effect of a topical curcumin preparation (BIOCURCUMAX) on burn wound healing in rats, Journal of Pharmaceutical and Biomedical Sciences (JPBMS), Vol. 08, Issue 08
24.	The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training, J Equine Vet Sci. 2012 December;32(12):805-15
25.	Evaluation of Antiepileptic and Memory Retention Activity of Curcumin Per SE and in Combination with Antiepileptic Drugs, Asian J Pharm Clin Res. 2014;6(2):145-148
26.	Anti-inflammatory activity of BCM-95® (CURCUGREEN®)(bio-enhanced formulation of turmeric with increased bioavailabilty) compared to Curcumin in Wistar rats, Pharmacognosy Journal, Vol 8, Issue 4, Jul-Aug, 2016 380 -384
27.	Systematic and comprehensive investigation of the toxicity of curcuminoid-essential oil complex: A bioavailable turmeric formulation, MOLECULAR MEDICINE REPORTS 13: 592-604, 2016
28.	Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults, British Journal of Nutrition, Volume 115, Issue 12, June 2016, pp. 2106-2113
29.	Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study; Hejazi J, Rastmanesh R, Taleban FA, Molana SH, Hejazi E, Ehtejab G, Hara N; Nutr Cancer. 2016;68(1):77-85. doi: 10.1080/01635581.2016.1115527.
30.	A randomized double-blind placebo-controlled phase IIB trial of curcumin in oral leukoplakia, DOI: 10.1158/1940-6207.CAPR-15-0390 Published 7 June 2016
31.	The efficacy and safety of a combination of glucosamine hydrochloride, chondroitin sulfate and bio-curcumin with exercise in the treatment of knee osteoarthritis: a randomized, double-blind, placebo-controlled study, European Journal of Physical and Rehabilitation Medicine [2016, 52(3):321-330]
32.	Short Report of a Preliminary Open Study of Synofit-Containing Bio-Curcumin, Greenlipped Mussel and Blackcurrant Leaf Extract in Arthritis, Open Journal of Rheumatology and Autoimmune Diseases, 5, 113-117. doi: 10.4236/ojra.2015.54018.
33.	Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo-controlled study. Lopresti AL, Drummond PD, J Affect Disord. 2017; 207:188-196. doi: 10.1016/j.jad.2016.09.047.
34.	Effect of Infla-Kine supplementation on the gene expression of inflammatory markers in peripheral mononuclear cells and on C-reactive protein in blood. J Transl Med. 2017 Oct 20;15(1):213. doi: 10.1186/s12967-017-1315-4.
35.a.	Risperidone-induced metabolic dysfunction is attenuated by Curcuma longa extract administration in mice; Metab Brain Dis, DOI 10.1007/s11011-017-0133-y (online )
35.b.	Risperidone-induced metabolic dysfunction is attenuated by Curcuma longa extract administration in mice. Metabolic brain disease. 2018 Feb 1;33(1):63-77.
36.	Curcumin and metformin-mediated chemoprevention of oral cancer is associated with inhibition of cancer stem cells. Molecular Carcinogenesis. 2017; 56:2446–2460.
37.	Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis, Scientific Reportsvolume 7, Article number: 814 (2017)
38.	Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study, BMC Complementary and Alternative Medicine, 2018 18:7
39.	Suppression of Proliferation and Invasive Behavior of Human Metastatic Breast Cancer Cells by Dietary Supplement BreastDefend. J Jiang, R Wojnowski, A Jedinak… – Integrative Cancer Therapies 10(2) 192–200(2011)
40.	Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaidTM: Mechanism of activity. Jia hua Jiang, Isaac Eliaz and Dani el Sliva international journal of oncology 38: 1675-1682, 2011
41.	ProstaCaid Induces G2/M Cell Cycle Arrest and Apoptosis in Human and Mouse Androgen– Dependent and – Independent Prostate Cancer Cells. Integrative Cancer Therapies 9(2) 186–196
42.	Comparative bioavailability of curcumin, turmeric and Biocurcumax™ in traditional vehicles using non-everted rat intestinal sac model. J Funct Foods. 2010;2(1):60–5
43.	Clinical Evaluation Of A Herbal Formulation, Rhulief™, In The Management Of Knee Osteoarthritis. Osteoarthritis And Cartilage. 2011 Sep 1;19:S145-6
44.	Effect of Biocurcumax TM Curcumin (BCM-95® (CURCUGREEN®)) On Treatment of Moderate Chronic Periodontitis. Journal of Mazandaran University of Medical Sciences. 2018 Mar 15;27(158):45-55.
45.	Role of curcumin as an adjuvant in treatment of advanced head and neck squamous cell carcinoma. Int J Otorhinolaryngol Head Neck Surg 2018;4:1388-93
46.a.	Evaluation Of Hepatoprotective Activity Of Combination Of Phyllanthus Niruri And Curcuma Longa Extracts In Wistar Rats. (POSTER)
46.b.	Evaluation of Hepatoprotective activity of combination of Phyllanthus niruri and Curcuma longa extracts in Wistar rats. Res. J. Pharm., Biol. Chem. Sci. 2012:1260-1268
46.c.	Hepatoprotective activity of combination of Phyllanthus niruri and Curcuma longa extracts against ethanol induced toxicity in wistar rats. International Journal of Pharma and Bio Sciences. 2016;7(1):P12-8.
47.	Curcumin Inhibits Polycomb Repressive Complex 2 through lncRNA-PVT1 and Enhances Gemcitabine Sensitivity in Chemoresistant Pancreatic Cancer. Gastroenterology. 2016 Apr 1;150(4):S624.
48.a.	Impact of a 3-weeks randomized double-blind cross-over study curuminoid supplementation on endotoxemia, inflammatory markers, and lipid profiles in healthy overweight and obese adults. Proceedings of the Nutrition Society. 2016;75(OCE3).
48.b.	Impact of a 3-weeks randomized double-blind cross-over study curuminoid supplementation on endotoxemia, inflammatory markers, and lipid profiles in healthy overweight and obese adults. Proceedings of the Nutrition Society. 2016;75(OCE3).
48.c.	Polyphenol curcuminoids and prevention of endotoxaemia and low-grade inflammation (Doctoral dissertation, University of Glasgow).
49.	Curcumin inhibits cancer-associated fibroblast-driven prostate cancer invasion through MAOA/mTOR/HIF-1α signaling. International journal of oncology. 2015 Dec 1;47(6):2064-72.
50.	ProstaCaid™ inhibits tumor growth in a xenograft model of human prostate cancer. International journal of oncology. 2012 May 1;40(5):1339-44.
51.	BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer. Oncology reports. 2012 Oct 1;28(4):1139-45.
52.a.	Curcumin supplementation mitigates NASH development and progression in female Wistar rats. Physiological reports. 2018 Jul;6(14):e13789.
52.b	Curcumin Supplementation Mitigates Nash Development and Progression in Female Wistar Rats: 2926 Board# 209 June 1 3. Medicine & Science in Sports & Exercise. 2018 May 1;50(5S):724.
53.	Oral Bioavailability of BCM-95® (CURCUGREEN®) in Dogs” Poster presentation. 2009 ACVIM Forum/ Canadian VMA Convention: June 3-6, 2009;Montréal, Québec, Canada
54.	A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer. Scientific reports. 2018 Sep 14;8(1):13869.
55.	Curcumin downregulates expression of opioid-related nociceptin receptor gene (OPRL1) in isolated neuroglia cells. Phytomedicine. 2018 Nov 15;50:285-99.
56.	The effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver disease. European journal of clinical nutrition. 2019 Jan 4:1.
57	Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study. Trials. 2019;20(1):214.
58.	The effects of curcumin supplementation on high‐sensitivity C‐reactive protein, serum adiponectin, and lipid profile in patients with type 2 diabetes: A randomized, double‐blind, placebo‐controlled trial. Phytotherapy Research. 2019 Mar 12.
59.	Evaluation of Antinociceptive Activity of BCM-95® (CURCUGREEN®) and Bospure® in Rodents. Indian Journal of Pharmacology, December 2013, Volume 45, Supplement S187.
60.	The effect of curcumin supplementation on anthropometric indices, insulin resistance and oxidative stress in patients with type 2 diabetes: a randomized, double-blind clinical trial. Diabetology & metabolic syndrome. 2019 Dec;11(1):41.
61.	Effect of curcumin supplementation on serum expression of select cytokines and chemokines in a female rat model of nonalcoholic steatohepatitis. BMC research notes. 2019 Dec;12(1):1-7
62.	Comparing different non-invasive methods in assessment of the effects of curcumin on hepatic fibrosis in patients with non-alcoholic fatty liver disease. Gastroenterology and hepatology from bed to bench. 2018;11(Suppl 1):S8.
63.	Curcumin and inflammation in non-alcoholic fatty liver disease: a randomized, placebo controlled clinical trial. BMC gastroenterology. 2019 Dec;19(1):133.
64.	Role of turmeric extract in minimising mucositis in patients receiving radiotherapy for head and neck squamous cell cancer: a randomised, placebocontrolled trial. J Laryngol Otol 2020;1–6
65.	Evaluation of the articular cartilage in the knees of rats with induced arthritis treated with curcumin. PLoS ONE. 2020; 15(3): e0230228. https://doi. org/10.1371/journal.pone.0230228
66.	Farhana L, Sarkar S, Nangia-Makker P, Yu Y, Khosla P, Levi E, et al. (2020) Natural agents inhibit colon cancer cell proliferation and alter microbial diversity in mice. PLoS ONE 15(3): e0229823. https://doi.org/10.1371/journal.pone.0229823
67.	Shep D, Khanwelkar C, Gade P, Karad S. Efficacy and safety of combination of curcuminoid complex and diclofenac versus diclofenac in knee osteoarthritis: a randomized trial. Medicine 2020;99:16(e19723).
68.	Shep D, Khanwelkar C, Gade P, Karad S. A Randomized Controlled Trial Of Curcumin And Diclofenac Combination In Knee Osteoarthritis. Int J Curr Pharm Sci [Internet]. 2019nov.15 [Cited 2020may4];11(6):111-4. DOI: https://dx.doi.org/10.22159/ijcpr.2019v11i6.36355
69.	Lopresti AL, Smith SJ, Metse AP, Foster T, Drummond PD. The Feasibility and Efficacy of a Brief Integrative Treatment for Adults With Depression and/or Anxiety: A Randomized Controlled Trial. Journal of Evidence-Based Integrative Medicine. 2020 Jul 7;25:2515690X20937997.
70	Banji D, Banji OJ, Srinivas K. Neuroprotective Effect of Turmeric Extract in Combination with Its Essential Oil and Enhanced Brain Bioavailability in an Animal Model. BioMed Research International. 2021 Jan 27;2021.
71.	Qu J, Mélot C, Appelboom T. Synofit Premium in Refractory Low Back Pain: A Retrospective Observational Study. Open Journal of Rheumatology and Autoimmune Diseases. 2017;7(02):120.
72.	Einbond LS, Zhou J, Wu HA, Mbazor E, Song G, Balick M, DeVoti JA, Redenti S, Castellanos MR. A novel cancer preventative botanical mixture, TriCurin, inhibits viral transcripts and the growth of W12 cervical cells harbouring extrachromosomal or integrated HPV16 DNA. British Journal of Cancer. 2020 Dec 1:1-3.
73.	Singhal, S., Hasan, N., Nirmal, K. et al. Bioavailable turmeric extract for knee osteoarthritis: a randomized, non-inferiority trial versus paracetamol. Trials 22, 105 (2021). https://doi.org/10.1186/s13063-021-05053-7
74.	Ortiz-Romero P, Egea G, Perez-Jurado LA, Campuzano V. Verapamil/Curcumin treatment attenuates the behavioral alterations observed in Williams Syndrome mice by regulation of MAPK pathway and Microglia overexpression. bioRxiv. 2021 Jan 1.
75.	Anti-SASP and anti-inflammatory activity of resveratrol, curcumin and β-caryophyllene association on human endothelial and monocytic cells. Biogerontology 22, 297–313 (2021). https://doi.org/10.1007/s10522-021-09915-0 .
76	Curcugreen Treatment Prevented Splenomegaly and Other Peripheral Organ Abnormalities in 3xTg and 5xFAD Mouse Models of Alzheimer’s Disease
77	The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects

78	A Randomized, Placebo-Controlled Study to Evaluate the Effect of Bio-Enhanced Turmeric Formulation on Radiation-Induced Oral Mucositis.
79	Curcuma longa and Boswellia Serrata for improving functional status in osteoarthritis patients: From bench to bedside evidences.
80	Antidiabetic effect of bio-enhanced preparation of turmeric in streptozotocin-nicotinamide induced type 2 diabetic Wistar rats.

81 .	Potential Therapeutic Effects of Curcuma longa extract in Patients with Osteoarthritis: A Randomized Controlled Trial
82	A Randomized Controlled Trial of Curcuma Longa and Boswellia Serrata Extract in Osteoarthritis.
83	The benefit of Curcuma longa and Boswellia serrata to improve quality of life in osteoarthritis patients: a randomized controlled trial.

84	Anti-SASP and anti-inflammatory activity of resveratrol, curcumin and β-caryophyllene association on human endothelial and monocytic cells. Biogerontology 22, 297–313 (2021). https://doi.org/10.1007/s10522-021-09915-0 .
85	Curcumin and zinc co-supplementation along with a loss-weight diet can improve lipid profiles in subjects with prediabetes: a multi-arm, parallel-group, randomized, double-blind placebo-controlled phase 2 clinical trial
86	Curcumin as adjuvant therapy to improve remission in myeloma patients: A pilot randomized clinical trial